Hand & Wrist

• September 22, 2026

  What is the evidence for perioperative administration of duloxetine in patients undergoing total knee or hip arthroplasty for postoperative pain management and narcotic consumption reduction?

  Zhong H, Li J, Chen Y, Huang Y, Wen Z, Zhao J. Effect of duloxetine on pain and opioid consumption after total knee and hip arthroplasty: a systematic review and meta-analysis of randomized controlled trials. Int J Clin Pharm. 2024 Feb;46(1):14-25. doi: 10.1007/s11096-023-01593-x. Epub 2023 Jun 9. PMID: 37294475.
• September 12, 2025

  What is the evidence for symptom reduction and functional improvements after corticosteroid injections in patients with carpal tunnel syndrome?

  Local corticosteroid injection vs placebo for carpal tunnel syndrome. Ashworth NL, Bland JDP, Chapman KM, Tardif G, Albarqouni L, Nagendran A. Local corticosteroid injection versus placebo for carpal tunnel syndrome. Cochrane Database Syst Rev. 2023 Feb 1;2(2):CD015148. doi: 10.1002/14651858.CD015148. PMID: 36722795; PMCID: PMC9891198.
• September 12, 2025

  What is the evidence for extracorporeal shock-wave therapy on pain reduction in patients with various tendinopathies?

  Majidi L, Khateri S, Nikbakht N, Moradi Y, Nikoo MR. The effect of extracorporeal shock-wave therapy on pain in patients with various tendinopathies: a systematic review and meta-analysis of randomized control trials. BMC Sports Sci Med Rehabil. 2024 Apr 24;16(1):93. doi: 10.1186/s13102-024-00884-8. PMID: 38659004; PMCID: PMC11041007.
• September 3, 2025

  What is the evidence for electrical bone stimulation for healing, pain management, and functional improvement in patients with fractures?

  Aleem IS, Aleem I, Evaniew N, Busse JW, Yaszemski M, Agarwal A, Einhorn T, Bhandari M. Efficacy of Electrical Stimulators for Bone Healing: A Meta-Analysis of Randomized Sham-Controlled Trials. Sci Rep. 2016 Aug 19;6:31724. doi: 10.1038/srep31724. PMID: 27539550; PMCID: PMC4990885.
• September 21, 2019

  What is the evidence for corticosteroid injections for trigger finger?

  Huisstede BM, Gladdines S, Randsdorp MS, Koes BW. Effectiveness of Conservative, Surgical, and Postsurgical Interventions for Trigger Finger, Dupuytren Disease, and De Quervain Disease: A Systematic Review. Arch Phys Med Rehabil. 2018 Aug;99(8):1635-1649.e21. PubMed PMID: 28860097.
• September 20, 2019

  What is the evidence for corticosteroid injections for deQuervain’s tenosynovitis?

  Ashraf MO, Devadoss VG. Systematic review and meta-analysis on steroid injection therapy for de Quervain's tenosynovitis in adults. Eur J Ortho Surg Traumatol. 2014 Feb;24(2):149-57. doi: 10.1007/s00590-012-1164-z. Epub 2013 Jan 22. Review. PubMed PMID: 23412309.
  
• October 6, 2018

  What is the evidence for IV Ketamine infusion for complex regional pain syndrome?

  Zhao J, Wang Y, Wang D. The Effect of Ketamine Infusion in the Treatment of Complex Regional Pain Syndrome: a Systemic Review and Meta-analysis. Curt Pain Headache Rep. 2018 Feb 5;22(2):12. doi: 10.1007/s11916-018-0664-x. Review. PubMed PMID: 29404715.
• May 26, 2015

  What is the evidence for conservative (non-surgical) measures to treat carpal tunnel syndrome?

  Huisstede BM1, Hoogvliet P, Randsdorp MS, Glerum S, van Middelkoop M, Koes BW. Carpal tunnel syndrome. Part I: effectiveness of nonsurgical treatments--a systematic review., Arch Phys Med Rehabil. 2010 Jul;91(7):981-1004.
  
• November 30, 2014

  What is the evidence for PRP injection for the treatment of soft tissue injuries?

  Moraes, V. Y., M. Lenza, M. J. Tamaoki, F. Faloppa and J. C. Belloti (2014). "Platelet-rich therapies for musculoskeletal soft tissue injuries." Cochrane Database Syst Rev 4: CD010071.